Comparative Analysis of NTG-Pd/Pa and Saline-Pd/Pa (CANS)

The goal of this observational study is to compare the value of NTG-Pd/Pa and saline-Pd/Pa in participants with intermediate stenosis of the coronary artery. The main questions it aims to answer are: The numerical difference between NTG-Pd/Pa and saline-Pd/Pa To compare the diagnostic performance of NTG-Pd/Pa and saline-Pd/Pa in predicting the binary result of FFR assessment? Participants will undergo NTG-Pd/Pa, Saline-Pd/Pa, and FFR successively in the target vessel.

NCT Number	NCT07195968
Lead Sponsor	National Taiwan University Hospital Collaborators: Miaoli General Hospital, Ministry of Health and Welfare, Taiwan, Taichung Veterans General Hospital
Conditions	Coronary Artery Disease
Enrollment	50 participants
Start Date	2025-09-17
Primary Completion	2027-05-31 (estimated)
Study Completion	2029-12-31 (estimated)
Updated on ClinicalTrials.gov	2025-09-29