Testing YAG Laser Iridotomy for Primary Angle-Closure Glaucoma

This study evaluates the effectiveness and safety of YAG laser peripheral iridotomy performed at two different locations (temporal and inferior) in patients with primary angle-closure glaucoma, a leading cause of blindness worldwide. Patients visiting the glaucoma clinic at Feiz Hospital who are candidates for peripheral iridotomy will participate. In each patient, one eye will receive a temporal iridotomy, and the other eye will receive an inferior iridotomy, with patients unaware of the location used in each eye. The study will measure outcomes such as laser power, intraocular pressure, visual symptoms, and complications over six months to determine which approach is more effective and safer.

NCT Number	NCT07195370
Lead Sponsor	Isfahan University of Medical Sciences
Conditions	Glaucoma Eye, Angle Closure Glaucoma
Enrollment	150 participants
Start Date	2025-05-01
Primary Completion	2025-10-01 (estimated)
Study Completion	2026-01-01 (estimated)
Updated on ClinicalTrials.gov	2025-09-26