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NOPE37: Angiogenic Factors for Managing Term Preeclampsia

Study acronym: NOPE37
StatusRecruiting
PhaseNot applicable
Started
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Record History

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  1. Trial status: Not Yet Recruiting to Recruiting
    • Study sites: 1 to 23
    • Start date changed from estimate of Dec 1, 2025 to Dec 4, 2025
    v3
  2. Start date: Oct 20, 2025 to Dec 1, 2025
    • Secondary endpoints: 14 to 13
    v2
  3. Study First Submitted
  • Stopped: an ongoing trial was terminated, suspended or withdrawn.
  • Notable: the trial’s plan changed such as a big move in its timeline or size, a new primary endpoint, sponsor or phase, or recruiting opened or resumed.
  • Minor: routine progress and housekeeping, such as sites added or enrollment closed.
This study tests the hypothesis that, in women with preeclampsia without severe features, delivery management based on sFlt-1/PlGF would reduce the rate of induction of labor without worsening the rate of progression to preeclampsia with severe features and other maternal complications.
Trial Details
NCT Number NCT07193680
Lead Sponsor Hospital Universitari Vall d'Hebron Research Institute
Collaborators: Instituto de Salud Carlos III
Conditions
(from sponsor)		 Preeclampsia
Related terms Pre-Eclampsia
Enrollment 750 participants
Start Date
Primary Completion (estimated)
Study Completion (estimated)
Updated on ClinicalTrials.gov