Clinical Trial

Impact of Chronic and Acute Caffeine Intake on the Hematopoietic System

Study acronym: CaffeineHSC
Recruiting
View on ClinicalTrials.gov →
Summary
This study investigates how caffeine intake affects blood stem and progenitor cells in healthy adults. The trial will compare people who regularly consume caffeine with those who consume very little or none. All participants will receive a single 200 mg caffeine tablet (similar to one cup of coffee) under fasting conditions. Blood samples will be collected before and three hours after caffeine intake. The study will assess whether caffeine influences the mobilization of blood stem and progenitor cells from the bone marrow into the bloodstream. It will also examine the effects of caffeine on the function, gene activity, and metabolism of blood cells.
Protocol Amendment History 2 amendments
This ClinicalTrials.gov record has been amended 2 times since 2025-09-18; most recent amendment 2026-07-02.
Status change: Not Yet Recruiting → Recruiting 2026-07-02
Trial Details
NCT Number NCT07193264
Lead Sponsor Jasmin Rettkowski
Collaborators: ETH Zurich, Laboratory of Stem Cell Biology and Ageing, ETH Zurich, Prof. Nina Cabezas-Wallscheid, Prof. Dr. Nina Cabezas-Wallscheid, ETH Zurich
Conditions Healthy Adults; Hematopoietic System; Caffeine
Enrollment 100 participants
Start Date 2025-11-05
Primary Completion 2027-12 (estimated)
Study Completion 2028-06 (estimated)
Updated on ClinicalTrials.gov 2026-07-06