G-CSF-Induced Bone Pain and Supportive Care Approaches

This prospective observational study aims to evaluate bone pain and related symptoms in patients with solid tumors receiving granulocyte colony-stimulating factor (G-CSF) during chemotherapy. A total of 128 patients will be enrolled at Ankara Etlik City Hospital. Pain severity will be assessed using the Visual Analog Scale (VAS), and supportive care strategies such as analgesics and non-pharmacological approaches will be documented. Patient-reported outcomes, including quality of life, fatigue, anxiety, depression, and sleep quality, will also be evaluated before and one week after G-CSF administration. The findings are expected to provide practical insights into the management of G-CSF-induced bone pain and improve supportive care practices.

NCT Number	NCT07192770
Lead Sponsor	Ankara Etlik City Hospital
Conditions	Solid Tumors, Chemotherapy-induced Neutropenia
Enrollment	225 participants
Start Date	2025-09-27
Primary Completion	2026-02-19 (estimated)
Study Completion	2026-02-19 (estimated)
Updated on ClinicalTrials.gov	2026-02-20