Clinical Trial

Self-sampling to Optimize Anal Lesion Outcomes

Study acronym: SOLO
Recruiting
View on ClinicalTrials.gov →
Summary
The purpose of this research study is to find ways to increase anal cancer screening among people at increased risk for anal cancer. This study will try to find out if persons will do an intervention (self-sampling of the anal canal) and if it affects cytology and high-resolution anoscopy (HRA) appointment attendance. Secondarily, the study will assess if a person who gets their choice of either self-sampling or healthcare provider sampling affects clinic attendance.
Protocol Amendment History 4 amendments
This ClinicalTrials.gov record has been amended 4 times since 2025-09-23; most recent amendment 2026-05-11.
Status change: Not Yet Recruiting → Recruiting 2025-11-10
Trial Details
NCT Number NCT07192055
Lead Sponsor Medical College of Wisconsin
Collaborators: National Cancer Institute (NCI), University of Chicago, Froedtert Hospital, M.D. Anderson Cancer Center
Conditions Anal Cancer
Enrollment 572 participants
Start Date 2025-11-18
Primary Completion 2028-03-31 (estimated)
Study Completion 2029-03-31 (estimated)
Updated on ClinicalTrials.gov 2026-05-12