Clinical Trial

Testing Personalized High-Definition Transcranial Direct Current Stimulation (HD-tDCS) as a Treatment of Posterior Cortical Atrophy

Study acronym: PCA
Recruiting
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Summary
This study is being completed to learn if high-definition transcranial direct current stimulation (HD-tDCS) has an effect on visual and thinking abilities in persons with posterior cortical atrophy (PCA). Participants will be randomized to receive real or sham HD-tDCS (8 sessions over 4 days). Following the randomized treatment, participants will have optional open-label phase with real HD-tDCS up to 26 weeks and other possible testing.
Protocol Amendment History 2 changes
notable Primary completion moved earlier: 2029-09 -> 2029-07-31 2026-07-01
minor Completion moved earlier: 2029-09 -> 2029-07-31 2026-07-01
Trial Details
NCT Number NCT07191327
Lead Sponsor University of Michigan
Conditions Posterior Cortical Atrophy
Enrollment 50 participants
Start Date 2026-01-28
Primary Completion 2029-07-31 (estimated)
Study Completion 2029-07-31 (estimated)
Updated on ClinicalTrials.gov 2026-06-30