Predictive Factors and Monitoring Strategies in Steroid-Induced Diabetes

Glucocorticoids are widely used in the management of autoimmune, inflammatory and neoplastic conditions. However, they are associated with significant metabolic effects, including steroid-induced diabetes (SID). SID is typically diagnosed using general criteria for type 2 diabetes, which may be inadequate due to the unique glycemic profile often seen in SID, where postprandial hyperglycemia predominates. This research aims to explore the diagnostic value of CGM during steroid therapy and identify risk factors for SID This is a prospective observational study (n=250) enrolling adults initiating glucocorticoid therapy. Participants will undergo 14-day continuous glucose monitoring (CGM) to assess predictive factors and glycemic profile.

NCT Number	NCT07190378
Lead Sponsor	Medical University of Warsaw
Conditions	Steroid-Induced Diabetes, Diabete Type 2, Steroid Induced Hyperglycemia
Enrollment	250 participants
Start Date	2025-06-20
Primary Completion	2028-06-05 (estimated)
Study Completion	2028-06-19 (estimated)
Updated on ClinicalTrials.gov	2025-10-01