Clinical Trial

Behavioral Impact and Neural Correlates of Network-based Brain Stimulation in Schizophrenia

Completed
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Summary
The primary aims of this study are to investigate the behavioral effects of applying targeted transcranial magnetic stimulation (TMS) to a node of the brain network subserving attention in schizophrenia and schizoaffective disorder and to correlate these effects to changes in brain network connectivity. Assumptions: -Cerebral activity can be investigated through the correlated activity of cortical nodes that constitute functional brain networks -Behavior can be correlated to the strength of correlated activity between and within nodes of these cortical networks -TMS to targeted nodes leads to changes in patterns of activity in these cortical networks Hypothesis: TMS to a node of the attention network in schizophrenia or schizoaffective disorder will influence network connectivity leading to measurable and predictable effects on attention.
Trial Details
NCT Number NCT07190352
Lead Sponsor Beth Israel Deaconess Medical Center
Conditions SCHIZOPHRENIA 1 (Disorder), Nicotine Use
Enrollment 15 participants
Start Date 2021-10-04
Primary Completion 2022-10-03 (estimated)
Study Completion 2022-10-03 (estimated)
Updated on ClinicalTrials.gov 2026-07-30