Clinical Trial

Effect of BIS-Guided Anesthesia on Postoperative Nausea and Vomiting in Pediatric Patients

Completed
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Summary
This randomized controlled trial will evaluate the effect of bispectral index (BIS)-guided anesthesia on postoperative nausea and vomiting (PONV) in children aged 3-8 years undergoing elective adenoidectomy. Fifty-eight patients will be randomized to BIS-guided anesthesia (target 40-60) or standard clinical management. The primary outcome is PONV incidence within 24 hours. Secondary outcomes include antiemetic use, emergence time, hospital stay, and parental satisfaction.
Protocol Amendment History 4 amendments
This ClinicalTrials.gov record has been amended 4 times since 2025-09-19; most recent amendment 2026-02-10.
Status change: Recruiting → Completed 2026-01-20
Status change: Not Yet Recruiting → Recruiting 2025-09-23
Trial Details
NCT Number NCT07189845
Lead Sponsor Engin Çetin
Conditions PONV, BIS
Enrollment 58 participants
Start Date 2025-09-24
Primary Completion 2026-01-20 (estimated)
Study Completion 2026-01-20 (estimated)
Updated on ClinicalTrials.gov 2026-02-12