Bleomycin Intralesional Injections of Cystic Hygromas

Thirty pediatric patients with cystic hygromas participated in this study. The cystic fluid was aspirated from the cystic hygroma, and the lesion was simultaneously injected with Bleomycin. Then, the lesion was re-injected at 4-week intervals until satisfactory results were obtained. Clinical response was evaluated as complete response (\> 90% reduction of lesion size), marked improvement (\>70% reduction of lesion size), moderate improvement (40 - 70% reduction of lesion size), slight improvement (\< 40%), and no response (\< 10% reduction of lesion size).

NCT Number	NCT07189832
Lead Sponsor	Delta University for Science and Technology
Conditions	Lymphatic Malformations
Enrollment	30 participants
Start Date	2024-09-01
Primary Completion	2025-04-01 (estimated)
Study Completion	2025-04-01 (estimated)
Updated on ClinicalTrials.gov	2026-04-28