Clinical Trial

Clinical Observation on the Efficacy of Patient-Donor Derived Probiotics in Improving Intestinal Flora Disorder in Patients With Intestinal Acute Graft-Versus-Host Disease (aGVHD)

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Record status
This record was last updated September 23, 2025 (before its estimated March 4, 2026 completion). Its status may not reflect the trial's current state.
Summary
To clinically evaluate the efficacy of patient- and/or donor-derived probiotics in ameliorating intestinal flora dysbiosis in patients with acute intestinal graft-versus-host disease (aGVHD), thereby mechanistically enhancing clinical outcomes and quality of life through intestinal microbiome modulation.
Trial Details
NCT Number NCT07188909
Lead Sponsor Institute of Hematology & Blood Diseases Hospital, China
Conditions Acute Graft-Versus-Host Disease
Enrollment 10 participants
Start Date 2025-09-15
Primary Completion 2026-03-04 (estimated)
Study Completion 2026-03-04 (estimated)
Updated on ClinicalTrials.gov 2025-09-23