SWE to Detect Enthesitis in PsA: Relationship With SIRT2 Expression and Disease Activity

1. To assess the diagnostic utility of shear-wave elastography (SWE), gray-scale (GS) ultrasound, and Power Doppler (PD) in detecting Patellar and Achilles tendinopathy in psoriatic patients with and without arthritis. 2. Investigate the relation between SWE, GS ultrasound, and PD finding and SIRT2 expression levels. 3. Evaluate the association of the imaging findings and SIRT2 levels with psoriatic arthritis disease activity score.

NCT Number	NCT07188688
Lead Sponsor	Assiut University
Conditions	Shear Wave Elastography
Enrollment	57 participants
Start Date	2025-10
Primary Completion	2026-10 (estimated)
Study Completion	2026-11 (estimated)
Updated on ClinicalTrials.gov	2025-09-23