Effect of High-intensity Interval Training Combined With DASH Diet on Arterial Stiffness in Hypertensive Patients

Cardiovascular disease (CVD) is one of the leading causes of mortality worldwide and a major risk factor for morbidity worldwide . It is necessary to reduce the incidence and risk factors of CVD, as physical activity is known to reduce mortality from CVD. Arterial stiffness and hypertension are closely related in pathophysiology. Chronic high blood pressure (BP) can lead to arterial wall damage by mechanical stress, endothelial dysfunction, increased inflammation, oxidative stress, and renin-angiotensin-aldosterone system (RAAS) activation. HIIT has been shown to be equally or even better at stimulating health benefits than moderate-intensity continuous training (MICT) and is considered a time-saving aerobic exercise for reducing arterial stiffness in HTN patients

NCT Number	NCT07188272
Lead Sponsor	Deraya University
Conditions	Hypertension, Arterial Stiffness
Enrollment	66 participants
Start Date	2025-07-10
Primary Completion	2025-12-10 (estimated)
Study Completion	2026-01-01 (estimated)
Updated on ClinicalTrials.gov	2026-06-03