Incidence of Pruritus Using Intrathecal Fentanyl Versus Epidural Fentanyl to Initiate Labour Analgesia.

The purpose of this study is to investigate the effect of neuraxial analgesia initiation on the incidence of pruritus in laboring women. Specifically, this study aim to compare intrathecal fentanyl with epidural fentanyl in order to determine whether the epidural route is associated with a lower occurrence and severity of pruritus. By clarifying these differences, the research seek to optimize analgesic strategies during labor while minimizing opioid-related side effects

NCT Number	NCT07187427
Lead Sponsor	St. Justine's Hospital
Conditions	Pruritis, Hypotension Drug-Induced, Urinary Retention, Fetal Bradycardia During Labor, Nausea and Vomitting, Satisfaction, Patient, Labor Analgesia, Neuraxial Opioid +4 more
Enrollment	80 participants
Start Date	2026-01
Primary Completion	2026-12 (estimated)
Study Completion	2027-05 (estimated)
Updated on ClinicalTrials.gov	2025-11-26