Clinical Trial

Autologous Fat Grafting in Upper Limb Burns Scars

Study acronym: BURNSCARCARE
Active, Not Recruiting
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Summary
Burn injuries are a complex form of trauma with a high risk of complications. When they affect the upper limbs, patients often develop functional contractures and/or pathological scars that significantly impair mobility, quality of life, and psychological well-being. Current treatments-such as surgical interventions and corticosteroid injections-offer limited effectiveness, require prolonged therapy, and are associated with discomfort, multiple sessions, and indirect costs. Autologous fat grafting, a regenerative technique based on the transfer of the patient's own adipose tissue, has emerged as a promising alternative. It combines biocompatibility with regenerative and anti-inflammatory properties that may improve both function and scar quality. This randomized clinical trial aims to evaluate the efficacy of fat grafting in patients with post-burn upper limb sequelae compared to standard treatment (surgical release and/or corticosteroid injections). Patients will be prospectively followed and assessed using validated scar scales and functional outcomes.
Trial Details
NCT Number NCT07186322
Lead Sponsor Federal University of São Paulo
Conditions Autologous Fat Grafting, Burn, Corticosteroid Injection
Enrollment 40 participants
Start Date 2025-07-01
Primary Completion 2026-12 (estimated)
Study Completion 2026-12-31 (estimated)
Updated on ClinicalTrials.gov 2025-09-22