Clinical Trial

Performance of Large Language Models for Structured Recognition and Refractive Prediction

Recruiting
View on ClinicalTrials.gov →
Summary
We conducted a single-center, retrospective observational study to evaluate large language models (ChatGPT 4o, GPT-5, DeepSeek) for automated interpretation of de-identified IOLMaster 700 reports provided as raster images. Models produced structured biometric extraction, toric IOL recommendation, and refractive predictions (sphere, cylinder, axis). Primary outcomes included parameter-level agreement and refractive error metrics; secondary outcomes included decision-support performance for toric IOL selection and agreement on ordered T-codes. No clinical intervention was performed.
Trial Details
NCT Number NCT07183891
Lead Sponsor Jin Yang
Conditions Cataract
Enrollment 100 participants
Start Date 2025-08-01
Primary Completion 2030-12-31 (estimated)
Study Completion 2035-12-31 (estimated)
Updated on ClinicalTrials.gov 2025-09-19