Clinical Trial

Determinants of Cardiorespiratory Fitness and Effects of HIIT in Patients With ANOCA Obstructive Coronary Artery Disease(ANOCA)

Recruiting
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Record status
This record was last updated September 19, 2025 (before its estimated March 30, 2026 completion). Its status may not reflect the trial's current state.
Summary
The main goal is to understand what causes reduced fitness in ANOCA and whether targeted exercise can help improve it. This study aims to better understand why patients with Angina and No Obstructive Coronary Artery Disease (ANOCA) have poor cardiorespiratory fitness and its effect on quality of life. Investigators also want to see if a structured high-intensity exercise program (HIIT), done with remote monitoring, can safely improve heart function, fitness, and quality of life in these patients. The Investigators will use a special exercise test called cardiopulmonary exercise testing to look for patterns that can help explain exercise limitations and quality of life in ANOCA before and after a remote high-intensity exercise program.
Trial Details
NCT Number NCT07182955
Lead Sponsor University of Virginia
Conditions MINOCA, Shortness of Breath, Atherosclerotic Heart Disease of Native Coronary Artery
Enrollment 25 participants
Start Date 2025-08-11
Primary Completion 2026-03-30 (estimated)
Study Completion 2026-04-14 (estimated)
Updated on ClinicalTrials.gov 2025-09-19