Fatigue in MS: From Invisible to Measurable

Fatigue is one of the most common and burdensome symptoms of MS, but its precise cause remains unknown, and an effective treatment is lacking. Previous research has shown that the progression of MS is associated with a higher presence of a specific type of T-cell, the cytotoxic CD4+ T-cells, which play a role in the immune system. The aim of this study is to investigate whether these cells can also be linked to fatigue in people with MS.

NCT Number	NCT07182903
Lead Sponsor	University Medical Center Groningen Collaborators: UHasselt
Conditions	Multiple Sclerosis
Enrollment	34 participants
Start Date	2025-10-27
Primary Completion	2026-04-02 (estimated)
Study Completion	2026-04-02 (estimated)
Updated on ClinicalTrials.gov	2026-04-20