Clinical Trial

Hypofractionated Radiotherapy Plus Immunochemotherapy for Neoadjuvant Treatment of Gastroesophageal Junction Adenocarcinoma

Recruiting Phase 1/2
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Summary
The purpose of this study is to investigate the safety and efficacy of HFRT plus neoadjuvant ICT in locally advanced resectable GEJA.
Protocol Amendment History 3 amendments
This ClinicalTrials.gov record has been amended 3 times since 2025-09-18; most recent amendment 2026-01-03.
Status change: Enrolling by Invitation → Recruiting 2026-01-03
Status change: Not Yet Recruiting → Enrolling by Invitation 2025-11-23
Trial Details
NCT Number NCT07182565
Lead Sponsor West China Hospital
Conditions Gastroesophageal Junction Adenocarcinoma, Hypofractionated Radiotherapy
Enrollment 84 participants
Start Date 2025-11-18
Primary Completion 2029-08-31 (estimated)
Study Completion 2029-08-31 (estimated)
Updated on ClinicalTrials.gov 2026-01-06