Brain Stimulation and Attention Control in Children With ADHD

The goal of this clinical trial is to learn if brain stimulation can help children ages 6 to 12 with attention-deficit/hyperactivity disorder (ADHD) improve their attention and self-control. The main questions it aims to answer are: Does intermittent theta burst stimulation (iTBS) improve performance on a task that tests attention and reaction times? Can brain activity and genetics help predict who benefits most from this treatment? Researchers will compare randomly assigned active iTBS to sham (inactive) stimulation groups to see if the treatment helps. Participants will: Receive 10 sessions of either active or sham iTBS over 2 weeks Complete a computer task measuring attention before and after stimulation Wear a brain cap during the task to record EEG signals, also take part in resting-state brain scans, namely magnetic resonance imaging (MRI) and functional near-infrared spectroscopy (fNIRS), and provide a saliva sample for genetic testing

NCT Number	NCT07182344
Lead Sponsor	Neurolab Plus Collaborators: Al-Farabi Kazakh National University
Conditions	ADHD - Attention Deficit Disorder With Hyperactivity
Enrollment	40 participants
Start Date	2025-09-04
Primary Completion	2026-03 (estimated)
Study Completion	2026-06 (estimated)
Updated on ClinicalTrials.gov	2025-09-19