Clinical Trial

Brain Stimulation and Sensory Integration in Children With ASD

Enrolling by Invitation
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Record status
This record was last updated September 19, 2025 (before its estimated March 2026 completion). Its status may not reflect the trial's current state.
Summary
The goal of this clinical trial is to find out if brain stimulation can help improve sensory integration in children ages 6 to 12 with autism spectrum disorder (ASD). The main questions it aims to answer are: Does brain stimulation using continuous theta-burst stimulation (cTBS) on bilateral dorsolateral prefrontal cortex (DLPFC) improve how children process sights and sounds together? Can brain functioning, structure, and genetics help predict who responds best to this treatment? Researchers will compare the results of the randomly assigned active brain stimulation to sham (inactive) stimulation groups to see if the treatment works. Participants will: Receive 10 sessions of either active or sham cTBS over 2 weeks Complete a sensory task involving flashes and beeps before and after stimulation Take part in brain scans, namely magnetic resonance imaging (MRI) and functional near-infrared spectroscopy (fNIRS), and provide a saliva sample for genetic testing
Trial Details
NCT Number NCT07182331
Lead Sponsor Neurolab Plus
Collaborators: Al-Farabi Kazakh National University
Conditions Autism Spectrum Disorder (ASD)
Enrollment 40 participants
Start Date 2025-08-25
Primary Completion 2026-03 (estimated)
Study Completion 2026-06 (estimated)
Updated on ClinicalTrials.gov 2025-09-19