Correlation Between the Midpalatal Suture Maturity and the Maxillary Third Molar Mineralization: a CBCT Study

Assessing the maturation of the mid-palatal suture is an essential criterion for orthodontic decision-making. However, from a CBCT according to Angelieri's classification , it remains difficult for the practitioner's untrained eye. As profile teleradiographs are almost routinely performed in orthodontic check-ups, numerous studies have looked for a correlation between the stage of maturation of the palatal suture and that of the cervical vertebrae. Some have also looked for a link with mineralization of mandibular third or second molars according to Demirjian's classification. These techniques would provide a reliable and reproducible method without the use of CBCT. In our study, the investigators will be looking for a correlation with mineralization of the maxillary third molar according to Nolla's classification. The latter has become common in practice and easy to apply on an orthopantomogram. This would simplify decision-making without the need for a CBCT, but by using the orthopantomogram which is already routinely performed during the assessment.

NCT Number	NCT07181707
Lead Sponsor	Central Hospital, Nancy, France
Conditions	Maturation of the Midpalatal Suture and Maxillary Third Molar Mineralization in Healthy Individuals
Enrollment	200 participants
Start Date	2026-01-01
Primary Completion	2026-03-26 (estimated)
Study Completion	2026-03-26 (estimated)
Updated on ClinicalTrials.gov	2026-04-30