Forward to Quit: A Person-centered Mobile Technology Intervention for Smoking Cessation Among Transgender Adults

This study evaluates the feasibility, acceptability, and preliminary efficacy of "Forward to Quit" (F2Q), a person-centered mobile health (mHealth) smoking cessation intervention designed specifically for transgender adults. The intervention was developed in collaboration with transgender individuals and gender-affirming healthcare providers. The study includes usability testing and a remote single-arm pilot trial. Primary outcomes include feasibility and acceptability of both the intervention and remote biochemical verification of smoking cessation. Secondary outcomes include self-reported and biochemically verified smoking cessation, as well as changes in psychosocial factors such as social support and gender affirmation. The goal is to inform a future large-scale trial and address tobacco-related health disparities in transgender populations.

NCT Number	NCT07181551
Lead Sponsor	University of Colorado, Denver Collaborators: National Institute on Drug Abuse (NIDA)
Conditions	Smoking Cessation
Enrollment	47 participants
Start Date	2025-10-14
Primary Completion	2026-03-25 (estimated)
Study Completion	2031-12 (estimated)
Updated on ClinicalTrials.gov	2026-06-30