New-Generation GMA Laryngeal Mask Airway Versus Conventional Inflatable Laryngeal Mask Airway

This study aims to compare the new-generation GMA laryngeal mask airway (LMA) with the traditional inflatable LMA in patients undergoing elective surgery under general anesthesia. The primary objectives are to evaluate the safety, effectiveness, stability, ease of use, and patient comfort of the GMA LMA, providing practical guidance for clinical airway management. Additionally, this research will analyze the anatomical positioning and sealing mechanism of the LMA to identify factors influencing proper alignment and airway sealing. The findings may contribute to future improvements in LMA design, enhancing patient safety and procedural success. This study is designed for healthcare providers, anesthesiologists, and researchers seeking evidence-based recommendations for LMA selection in clinical practice. Participation involves standard anesthesia procedures with close monitoring to ensure patient safety.

NCT Number	NCT07177586
Lead Sponsor	First Affiliated Hospital of Zhejiang University Collaborators: The Second Affiliated Hospital of Zhejiang Chinese Medical University, Red Cross Hospital, Hangzhou, China, Hangzhou Hospital of Traditional Chinese Medicine, Lanxi People's Hospital, Ningbo Medical Center Lihuili Hospital, The Second Affiliated Hospital of Jiaxing University, Taizhou Hospital of Zhejiang Province affiliated to Wenzhou Medical University, Ruijin Hospital, The Central Hospital of Lishui City, Lishui Country People's Hospital, Sir Run Run Shaw Hospital
Conditions	Supraglottic Airway Devices Position
Enrollment	1,384 participants
Start Date	2025-09-18
Primary Completion	2027-07-31 (estimated)
Study Completion	2027-07-31 (estimated)
Updated on ClinicalTrials.gov	2026-02-04