The PRE-VAIL Study

During the prone position, there may be an increase in intragastric pressure. The investigators focus on a scientific question: Whether reducing enteral nutrition before the prone position will benefit patients with severe mechanically ventilated acute respiratory distress syndrome (ARDS). The experimental group had the enteral nutrition dose reduced before the prone position, while the control group did not have the enteral nutrition dose reduced

NCT Number	NCT07176624
Lead Sponsor	The First Hospital of Jilin University
Conditions	ARDS (Moderate or Severe), Prone Position, Enteral Nutrition Feeding, Intensive Care Unit (ICU) Admission
Enrollment	259 participants
Start Date	2025-09-14
Primary Completion	2027-08-20 (estimated)
Study Completion	2028-02-20 (estimated)
Updated on ClinicalTrials.gov	2026-02-09