Revision of Deep Brain Stimulator in Patients With Parkinson's Disease

Parkinson's disease is a chronic and progressive neurodegenerative disease that affects the central nervous system, particularly impairing movement control. It is associated with the loss of dopamine-producing cells in the brain and typically occurs in middle age and beyond. Deep brain stimulation (DBS) is considered when symptoms of Parkinson's disease, such as tremors, slowed movements, and muscle rigidity, are not adequately controlled with medications. Selected patients with severe symptoms that do not respond to medical treatment are generally considered for this treatment. Battery revision surgeries can be performed under general anesthesia or regional anesthesia. Patients undergoing general anesthesia should be cautious about the potential complications of general anesthesia, while those undergoing regional anesthesia should be cautious about the local anesthetic systemic toxicity. Because each method has its own advantages, the choice of anesthesia may vary. This study aimed to compare postoperative analgesic efficacy and patient satisfaction in patients who underwent surgery under general anesthesia or sedation-assisted battery replacement under regional anesthesia. Both anesthesia methods are routinely used in Parkinson's disease patients undergoing battery replacement.

NCT Number	NCT07176494
Lead Sponsor	Ankara Etlik City Hospital
Conditions	Pain Management, Regional Anesthesia, Deep Brain Stimulation, Parkinsons Disease
Enrollment	50 participants
Start Date	2025-09-20
Primary Completion	2026-07-05 (estimated)
Study Completion	2026-07-20 (estimated)
Updated on ClinicalTrials.gov	2025-12-10