Adaptive Decision-making And Personalized Treatment for PTSD (ADAPT-PTSD)

By doing this research project, the investigators hope to learn which strategies work best to help veterans who are not benefiting from their first PTSD treatment or not completing between-session homework assignments regularly that might improve treatment response. The investigators also want to learn how best to match the right type and amount of treatment to each individual veteran. By conducting this research project, they hope to: * See if trying a different treatment strategy for veterans not responding to their first PTSD treatment would be more helpful * See if sending text message prompts between sessions encourages more completion of between-session homework

NCT Number	NCT07176273
Lead Sponsor	The University of Texas Health Science Center at San Antonio Collaborators: United States Department of Defense
Conditions	Posttraumatic Stress Disorder, PTSD
Enrollment	302 participants
Start Date	2025-12-12
Primary Completion	2028-05-22 (estimated)
Study Completion	2028-08-14 (estimated)
Updated on ClinicalTrials.gov	2025-12-19