Surfactant Using a Supraglottic Airway Device in Late Preterm to Early Term Infants

The purpose of this research is to learn new information that may help other infants that have respiratory distress syndrome and need breathing support after birth. The goal of this research is to see if continuous positive airway pressure (CPAP) alone or CPAP with surfactant administration through a less invasive method via an Airway Device (supraglottic airway device) temporarily placed above the vocal cords is better for treating respiratory distress syndrome in late preterm and early term infants.

NCT Number	NCT07176117
Lead Sponsor	Sharp HealthCare Collaborators: Chiesi USA, Inc.
Conditions	Respiratory Distress Syndrome (Neonatal), Surfactant
Enrollment	422 participants
Start Date	2025-11-20
Primary Completion	2030-12-31 (estimated)
Study Completion	2031-06-30 (estimated)
Updated on ClinicalTrials.gov	2026-07-13