Clinical Trial

Combination of COMBO Endoscopy Oropharyngeal Airway and HFNC Oxygenation in Sedated Gastrointestinal Endoscopy for Morbidly Obese Patients

Recruiting
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Summary
Hypoxaemia during sedated gastrointestinal endoscopy exceeds 40 % in morbidly obese (BMI ≥ 35 kg m-²) patients. High-flow nasal cannula alone often fails because of persistent airway collapse. A recent innovation in this domain is the COMBO Endoscopy Oropharyngeal Airway-a multifaceted device that encompasses capnography monitoring, bite block , oxygenation support, and oropharyngeal airway management.The purpose of this study is to investigate whether the combination of the COMBO Endoscopy Oropharyngeal Airway and High-Flow Nasal Cannula oxygenation reduces the incidence of hypoxemia in this population.
Protocol Amendment History 4 amendments
This ClinicalTrials.gov record has been amended 4 times since 2025-09-09; most recent amendment 2026-03-09.
Status change: Not Yet Recruiting → Recruiting 2026-01-01
Trial Details
NCT Number NCT07175155
Lead Sponsor Zhejiang University
Conditions Hypoxemia, Esophageal Cancer, Morbidly Obese Patients, Gastric Cancer
Enrollment 410 participants
Start Date 2025-10-24
Primary Completion 2027-08-20 (estimated)
Study Completion 2027-08-20 (estimated)
Updated on ClinicalTrials.gov 2026-03-11