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The Progressive Supranuclear Palsy Clinical Trial Platform

Study acronym: PTP
StatusRecruiting
PhasePhase 2
SponsorAdam Boxer
Started
View on ClinicalTrials.gov ↗

Record History

See every version on ClinicalTrials.gov ↗

  1. Minor Trial sites expanded: 12 → 18 locations
  2. Minor Study sites: 12 to 13
  3. Minor Trial sites expanded: 8 → 12 locations
  4. Minor Eligibility criteria expanded, about 27 words
    • Site details revised at 1 of 8 sites
    • Collaborators: details revised at 2 of 6 entries
    • Study description expanded, about 2 words
  5. Minor Trial sites expanded: 1 → 8 locationsv9
  6. Minor Re-verified, no change to tracked fieldsv8
  7. Notable Recruitment opened
    • Start date changed from estimate of Jun 30, 2026 to Jul 29, 2026
    • Site details revised
    v7
  8. Minor Study sites: 0 to 1v6
  9. Notable Primary and study completion dates: Jul 31, 2029 to Sep 28, 2030
    • Start date: Dec 1, 2025 to Jun 30, 2026
    v5
  10. Minor Interventions: AADvac1 (Biological), Treatment B (Drug) to AADvac1 (Biological), LM11A-31 (Drug)
    • Study description shortened, about 1 word
    v4
  11. Minor Interventions: AADvac1 (Biological), AZP006 (Ezeprogind®) (Drug) to AADvac1 (Biological), Treatment B (Drug)
    • Study description expanded, about 1 word
    v3
  12. Minor Re-verified, no change to tracked fieldsv2
  13. Minor Study First Submitted
  • Stopped: an ongoing trial was terminated, suspended or withdrawn.
  • Notable: the trial’s plan changed such as a big move in its timeline or size, a new primary endpoint, sponsor or phase, or recruiting opened or resumed.
  • Minor: routine progress and housekeeping, such as sites added or enrollment closed.
The Progressive Supranuclear Palsy Clinical Trial Platform (PTP) is a multi-center, multi-regimen clinical trial evaluating the safety and efficacy of investigational products for the treatment of PSP.
Trial Details
NCT Number NCT07173803
Lead Sponsor Adam Boxer
Collaborators: National Institute on Aging (NIA), Alzheimer's Therapeutic Research Institute, University of Southern California, Massachusetts General Hospital, University of California, San Diego, Alzheimer's Clinical Trials Consortium
Conditions
(from sponsor)
Progressive Supranuclear Palsy(PSP)
Related terms Supranuclear Palsy, Progressive
Enrollment 440 participants
Start Date
Primary Completion (estimated)
Study Completion (estimated)
Updated on ClinicalTrials.gov