The Effect of Bleaching Application Mode on Bleaching-induced Tooth Sensitivity.

The aim of this study is to evaluate the effect of single versus multiple application protocols for in-office dental bleaching using two different bleaching gels (Pola Office Plus, SDI, 37.5% HP and Opalescence Boost, Ultradent, 40% HP) on the risk and intensity of tooth sensitivity, as well as the effect of the application protocol on the bleaching efficacy. Null hypothesis: There is no difference in intensity and risk of tooth sensitivity between single and multiple application of each gel and the application protocol dose not present significant effect on the bleaching efficacy.

NCT Number	NCT07173296
Lead Sponsor	King Abdullah University Hospital Collaborators: Jordan University of Science and Technology
Conditions	Tooth Sensitivity
Enrollment	60 participants
Start Date	2025-01-01
Primary Completion	2026-09-01 (estimated)
Study Completion	2026-09-30 (estimated)
Updated on ClinicalTrials.gov	2025-09-15