Clinical Trial

Dynamic Impact of NIV on Diaphragmatic Ultrasound in Patients With Amyotrophic Lateral Sclerosis

Study acronym: EchoDia
Not Yet Recruiting
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Summary
The goal of this pilot observational study is to learn about the dynamic impact of the non invasive ventilation on the diaphragm in patient with amyotrophic lateral sclerosis. The main question it aims to answer : can diaphragmatic ultrasound detect differences in diaphragmatic motion (diaphragmactic excursion and diaphragmatic thickening between spontaneous breathing and non-invasive ventilation ? Participants will receive diaphragmatic ultrasound assessments both under spontaneous breathing and during non-invasive ventilation on their day hospital evaluation for ventilatory support.
Trial Details
NCT Number NCT07170865
Lead Sponsor University Hospital, Grenoble
Conditions Amyotrophic Lateral Sclerosis (ALS), Non Invasive Ventilation (NIV)
Enrollment 20 participants
Start Date 2025-09-01
Primary Completion 2026-09-15 (estimated)
Study Completion 2026-10-15 (estimated)
Updated on ClinicalTrials.gov 2025-09-12