Hyperbaric Oxygen Treatment for Necrotizing Fasciitis and Necrotizing Soft Tissue Infections

The goal of this clinical trial is to learn if hyperbaric oxygen is beneficial in treating necrotizing infections and decreasing rates of morbidity and mortality. This study therefore has two aims: 1. Determine if hyperbaric oxygen improve morbidity and mortality compared to standard of care using a prospective model. 2. Determine if faster diagnosis to debridement times negate the need for hyperbaric oxygen treatments in necrotizing infections.

NCT Number	NCT07170020
Lead Sponsor	Corewell Health West
Conditions	Necrotizing Fascitis
Enrollment	160 participants
Start Date	2025-11-14
Primary Completion	2026-11-14 (estimated)
Study Completion	2027-11-14 (estimated)
Updated on ClinicalTrials.gov	2025-09-12