Clinical Trial

Identifying Genetic Targets in Gynecological Tumors

Study acronym: GEN_EXP_CO2021
Recruiting
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Summary
This observational study aims to identfy genetic targets involved in the pathogenesis of gynecological tumors, with a focus on high-grade serous ovarian carcinoma. Using a triple approach - in silico, ex vivo and in vitro - the study will investigate the role of gonadotropins and their related signaling pathways in the epithelial ovarian cancers. Gene and protein expression levels will be evaluated through transcriptomic analysis, immunohistochemistry and functional assays on tumor cell lines. The goal is to uncover potential diagnostic or therapeutic targets in gynecological malignancies.
Protocol Amendment History 1 amendment
This ClinicalTrials.gov record has been amended once since 2025-09-09.
Trial Details
NCT Number NCT07169396
Lead Sponsor Azienda USL Reggio Emilia - IRCCS
Conditions Ovarian Cancer
Enrollment 180 participants
Start Date 2021-11-17
Primary Completion 2021-11-17 (estimated)
Study Completion 2027-11 (estimated)
Updated on ClinicalTrials.gov 2026-07-24