Track this trial free. DataLookout checks ClinicalTrials.gov daily and emails you which fields changed on NCT07168421 (status, enrollment, completion dates, endpoints, sites) when this record is updated. Free accounts track up to 5 trials.

Track this trial

LANdiolol to Avoid TAchycardia in Patients at Risk for Cardiovascular Events Undergoing Major Non-cardiac Surgery

Study acronym: LANTA-P
StatusRecruiting
PhasePhase 4
Started
View on ClinicalTrials.gov ↗

Record History

See every version on ClinicalTrials.gov ↗

  1. Trial status: Not Yet Recruiting to Recruiting
    • Start date changed from estimate of Oct 2025 to Apr 24, 2026
    • Site details revised
    • Eligibility criteria expanded, about 2 words
    v2
  2. Study First Submitted
  • Stopped: an ongoing trial was terminated, suspended or withdrawn.
  • Notable: the trial’s plan changed such as a big move in its timeline or size, a new primary endpoint, sponsor or phase, or recruiting opened or resumed.
  • Minor: routine progress and housekeeping, such as sites added or enrollment closed.
Limiting perioperative tachycardia (aiming for a heart rate \<90 beats per minute throughout the perioperative period) using the ultra-short acting beta-blocker landiolol in patients with cardiovascular risk factors undergoing major surgery might lower the incidence of perioperative myocardial injury. Feasibility of the intervention needs to be proven prior to conduction of a larger trial.
Trial Details
NCT Number NCT07168421
Lead Sponsor Insel Gruppe AG, University Hospital Bern
Conditions
(from sponsor)		 Perioperative Myocardial Injury, Autonomic Dysfunction, Cardiovascular (CV) Risk, Major Surgery, Beta Blocker, Myocardial Injury After Non-cardiac Surgery
Related terms Primary Dysautonomias
Enrollment 114 participants
Start Date
Primary Completion (estimated)
Study Completion (estimated)
Updated on ClinicalTrials.gov