Clinical and Radiological Evaluation of Total Ankle Replacement (ProtesiTT)

Numerous studies reported the efficacy of new third-generation of total ankle arthroplasties for the treatment of advanced ankle osteoarthritis and clinical results are comparable to ankle arthrodesis. The improvement in knowledge of ankle joint biomechanics, instrumentation, surgical approach may led to even higher clinical results in comparison to arthrodesis. Many of the studies reporting the results of ankle replacement are provided by surgeons involved at least in the initial design of the implant. Thus, familiarity with the system can be a potential bias affecting outcomes and orthopedic surgeons may find difficulties in reproducing the results. In this study, we will assess the clinical and radiological outcomes in patients who underwent this procedure performed by non-designer surgeons

NCT Number	NCT07168330
Lead Sponsor	I.R.C.C.S Ospedale Galeazzi-Sant'Ambrogio
Conditions	Orthopedic Disorder
Enrollment	100 participants
Start Date	2017-07-01
Primary Completion	2017-10-30 (estimated)
Study Completion	2027-12-31 (estimated)
Updated on ClinicalTrials.gov	2025-09-17