Clinical Trial

The Role of the LC-NA System in Experimental Sleep Fragmentation

Study acronym: DMTN_FragSleep
Recruiting Phase 1
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Summary
Sleep-wake regulation affects every person's life, yet the molecular mechanisms underlying these processes remain poorly understood. In particular, the microstructure of sleep has not been sufficiently studied to explain how sleep produces a feeling of restoration the following morning. Stress also plays a significant role in sleep regulation. This study aims to investigate the role of norepinephrine in these processes.
Protocol Amendment History 3 amendments
This ClinicalTrials.gov record has been amended 3 times since 2025-09-08; most recent amendment 2026-06-10.
Status change: Not Yet Recruiting → Recruiting 2026-06-10
Trial Details
NCT Number NCT07167316
Lead Sponsor Hans-Peter Landolt
Collaborators: Wellcome Trust
Conditions The Role of the LC-NA System in Sleep Regulation
Enrollment 42 participants
Start Date 2026-05-21
Primary Completion 2026-12-01 (estimated)
Study Completion 2027-10-01 (estimated)
Updated on ClinicalTrials.gov 2026-06-12