Clinical Trial

Exploring the Cognitive Benefits of a Blackcurrant-Based Supplement in Normobaric Hypoxia

Not Yet Recruiting
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Record status
This record was last updated September 10, 2025 (before its estimated December 25, 2025 completion). Its status may not reflect the trial's current state.
Summary
This study investigates the cognitive effects of Ārepa, a blackcurrant-based drink, under simulated high-altitude conditions (4,500m normobaric hypoxia for \~180 minutes). Using a double-blind, randomised, placebo-controlled crossover design, participants will consume either the nootropic blackcurrant-based drink or a taste-matched placebo. Cognitive testing (\~80 minutes) includes Trail-making, Stroop, N-back, Serial 7s/3s, and RVIP tasks. Physiological measures (heart rate, SpO₂, blood) and biomarkers (MAO-B, BDNF, hsCRP, S100B, Prolactin, C3G, Sarmentosin) will be assessed. Scales will evaluate mood, wellbeing, and perceived effects. The aim is to determine if the nootropic drink can support cognitive function in hypoxic environments.
Trial Details
NCT Number NCT07166835
Lead Sponsor Leeds Beckett University
Conditions Cognitive Performance, Executive Function (Cognition), Working Memory, Hypoxia Induced Cognitive Impairment, Mood
Enrollment 27 participants
Start Date 2025-09-01
Primary Completion 2025-12-25 (estimated)
Study Completion 2027-10-01 (estimated)
Updated on ClinicalTrials.gov 2025-09-10