Efficacy of Neoadjuvant Immunotherapy in Patients With Lung Cancer

The goal of this observational study is to learn about the long-term effects of neoadjuvant immunotherapy in patients with lung cancer. The main questions it aims to answer are: * Does pneumonectomy bring more benefits for pateints than lobectomy? * Does surgery bring more benefits for patients than non-surgery modalities (such as radiotherapy) after neoadjuvnat immunotherapy? Participants will receive neoadjuvant treatment and the study will analyze the data.

NCT Number	NCT07166003
Lead Sponsor	Cancer Institute and Hospital, Chinese Academy of Medical Sciences
Conditions	Lung Cancer, Non-Small Cell, Immunotherapy
Enrollment	500 participants
Start Date	2025-04-20
Primary Completion	2027-02-02 (estimated)
Study Completion	2030-04-14 (estimated)
Updated on ClinicalTrials.gov	2025-09-10