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CTCA Prior to Invasive Angiography in Post-Bypass Patients (BYPASS CTCA 2)

StatusRecruiting
PhaseNot applicable
Started
View on ClinicalTrials.gov ↗

Record History

  1. Primary completion pushed from Sep 30, 2027 to Jul 31, 2029v3 Show 4 more changesShow less
    • Recruitment opened
    • Study completion pushed from Nov 30, 2028 to Jul 31, 2029
    • Study sites: 0 to 1
    • Start date changed from estimate of Sep 30, 2026 to Apr 16, 2026
  2. Start date: Sep 30, 2025 to Sep 30, 2026v2
  3. Study First Submitted
  • Stopped: an ongoing trial was terminated, suspended or withdrawn.
  • Notable: the trial’s plan changed such as a big move in its timeline or size, a new primary endpoint, sponsor or phase, or recruiting opened or resumed.
  • Minor: routine progress and housekeeping, such as sites added or enrollment closed.
The goal of this clinical trial is to evaluate whether a coronary computed tomography angiography (CTCA)-guided strategy can reduce the risk of death, heart attack, stroke, and hospital admissions in patients experiencing angina or myocardial infarction following coronary artery bypass graft (CABG) surgery. The main questions it aims to answer are: * Can CTCA reduce major adverse cardiovascular events compared to standard invasive coronary angiography? * Is CTCA a cost-effective and safer alternative that improves patient quality of life? Researchers will compare outcomes between patients receiving CTCA prior to angiography and those undergoing standard angiography alone to determine if CTCA improves clinical outcomes and procedural safety. Participants will: * Be randomly assigned to either CTCA-guided care or standard angiography * Undergo coronary imaging and follow-up assessments * Complete questionnaires on quality of life and healthcare resource use
Trial Details
NCT Number NCT07165678
Lead Sponsor Queen Mary University of London
Collaborators: National Institute for Health Research, United Kingdom
Conditions
(from sponsor)		 Coronary Heart Disease
Related terms Angina Pectoris, Coronary Artery Disease, Coronary Disease
Enrollment 1,000 participants
Start Date
Primary Completion (estimated)
Study Completion (estimated)
Updated on ClinicalTrials.gov