Clinical Trial

Effect of Different Anesthetic Drugs on Electrocorticography (ECOG).

Study acronym: ECOG-Anaes
Active, Not Recruiting Phase 3
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Summary
Prospective, double-blind, randomized-controlled study for pediatric cases scheduled for brain tumor excision with the aid of electrocorticography (ECOG). Intraoperative ECOG has been used in an effort to localize the site of epileptogenicity through the demonstration of Interictal Epileptiform Discharges (IED) persistence, frequency, and distribution. During ECOG, pharmaco-activation may be required in order to activate Interictal Epileptiform Abnormalities (IEAs). Frequency of IEAs will be measured for each drug. The effects of anesthetic agents on intraoperative ECOG, as we assume that fentanyl will be superior to ketamine.
Trial Details
NCT Number NCT07165262
Lead Sponsor Children's Cancer Hospital Egypt 57357
Conditions Epilepsy, Brain Tumor
Enrollment 88 participants
Start Date 2025-08-18
Primary Completion 2027-03 (estimated)
Study Completion 2027-03 (estimated)
Updated on ClinicalTrials.gov 2025-09-10