Ganglion Resection Effectiveness Trial

The goal of this clinical trial is to learn if surgery helps with wrist ganglions in adults. The main question it aims to answer is: * Does surgery result in better patient-reported outcomes and satisfaction over a 6-months follow-up period? Researchers will compare surgery to conservative treatment (self-administered exercises and use of the hand as tolerated) to see if surgery provides superior outcomes. Participants will: * Be randomly assigned to receive either surgery or conservative treatment * Complete questionnaires about wrist pain, function, quality of life, satisfaction, and recovery at 3, 6, and 12 months

NCT Number	NCT07162415
Lead Sponsor	Tampere University Hospital Collaborators: Tampere University, Hospital Nova, Central Finland, National University Hospital, Singapore, Helsinki University Central Hospital
Conditions	Wrist Ganglion, Ganglion, Ganglion Cyst, Connective Tissue Disease, Mucinoses
Enrollment	220 participants
Start Date	2026-01-13
Primary Completion	2034-12 (estimated)
Study Completion	2035-12 (estimated)
Updated on ClinicalTrials.gov	2026-01-21