Vaccination Nudges From Pharmacists

The goal of this individual-level pragmatic randomized policy trial is to learn about the impact of behavioural nudges via mailed letters on increasing influenza and travel vaccination uptake in Alberta, Canada. The primary outcome is the proportion of adults receiving influenza and/or travel vaccination. The secondary outcome is the number of stroke events in the 6 months following vaccination. As such, this research aims to answer two key questions: 1. Do behavioural nudges increase influenza and travel vaccination in Alberta? 2. If yes, is there a decrease in the number of stroke events in the 6 months following vaccination? The two-arm individual level pragmatic randomized trial design includes two letter dimensions, a letter (a "nudge") with an influenza and cardiovascular risk reduction message and a letter with a travel vaccination benefit message, yielding the following groups: Letter with an influenza and cardiovascular risk reduction message Letter with a travel vaccination benefit message

NCT Number	NCT07161739
Lead Sponsor	University of Calgary Collaborators: Alberta Health services, Mint Health + Drugs
Conditions	Stroke, Influenza Human, Influenza Vaccines, Health Behavior Change, Travel-Related Illness
Enrollment	20,000 participants
Start Date	2025-11-06
Primary Completion	2026-09-01 (estimated)
Study Completion	2026-12-01 (estimated)
Updated on ClinicalTrials.gov	2026-02-10