Telerehabilitation in Central and Peripheral Neurological Sequelae From Chemotherapy

The goal of this clinical trial is to validate the use of innovative tele-rehabilitation (TR) models in terms of efficiency and effectiveness in a pilot cohort of subjects with central and peripheral chemotherapy-induced neurotoxicity. Participants will be randomized (with an allocation ratio of 1:1) into the experimental group (TRUST\_ME - 15 sessions of motor and cognitive activities delivered at home through a TR approach using the Maia platform) and Treatment as Usual (15 sessions of multimedia content of educational/rehabilitation activities delivered via telemedicine platfom). It expected that the TR system to be considered acceptable in terms of efficiency (usability and acceptability of the technologies) and clinically effective, with positive impacts on both quality of life and central and peripheral functioning in these patients.

NCT Number	NCT07159854
Lead Sponsor	Fondazione Don Carlo Gnocchi ETS Collaborators: Astir s.r.l.
Conditions	Chemotherapy-induced Neurotoxicity
Enrollment	60 participants
Start Date	2025-09-01
Primary Completion	2026-07-31 (estimated)
Study Completion	2026-08-31 (estimated)
Updated on ClinicalTrials.gov	2025-09-08