Clinical Trial

The Safety, Efficacy, and Immune Response of Multimodal Thermal Therapy in the Treatment of Malignant Liver Tumors

Recruiting
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Summary
Multimodal thermal therapy (MTT), as an initiative integration of cryotherapy and radiofrequency heating, has been applied to treat various solid tumors. The feasibility and safety for MTT in the treatment of malignant liver tumors is well-established. This prospective, multi-center, randomized controlled clinical study aimed to explore the ablation-induced immune activating response of MTT in the treatment of malignant liver tumors.
Protocol Amendment History 1 amendment
This ClinicalTrials.gov record has been amended once since 2025-09-05.
Status change: Not Yet Recruiting → Recruiting 2026-07-07
Trial Details
NCT Number NCT07159048
Lead Sponsor Fudan University
Collaborators: Shanghai Zhongshan Hospital, Ruijin Hospital
Conditions Hepatocellular Carcinoma, Colorectal Cancer Liver Metastasis
Enrollment 120 participants
Start Date 2025-10-15
Primary Completion 2026-10-31 (estimated)
Study Completion 2027-10-31 (estimated)
Updated on ClinicalTrials.gov 2026-08-10