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Efficacy of Methylprednisolone for Pain Control After ACL Repair

StatusRecruiting
PhasePhase 4
Started
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Record History

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  1. Start date changed from estimate of Oct 2025 to Oct 21, 2025v4
  2. Trial status: Enrolling by Invitation to Recruiting
    • Start date: Sep 2025 to Oct 2025
    • Study description revised
    • Site details revised
    v3
  3. Study title shortened, about 4 wordsv2
  4. Study First Submitted
  • Stopped: an ongoing trial was terminated, suspended or withdrawn.
  • Notable: the trial’s plan changed such as a big move in its timeline or size, a new primary endpoint, sponsor or phase, or recruiting opened or resumed.
  • Minor: routine progress and housekeeping, such as sites added or enrollment closed.
Opioids are commonly used after orthopedic surgery for pain control but have been shown to increase complications, surgeries, readmissions, and risk for opioid use disorder. The purpose of this study is to investigate the impact of adding a methylprednisolone taper to the pain regimen after ACL repair surgery to determine if this results in decreased postoperative pain and opioid use without increasing complications.
Trial Details
NCT Number NCT07158476
Lead Sponsor St. Louis University
Conditions
(from sponsor)		 ACL Surgery, Pain Management
Related terms Agnosia, Pain
Enrollment 90 participants
Start Date
Primary Completion (estimated)
Study Completion (estimated)
Updated on ClinicalTrials.gov