Clinical Trial

Gingival Crevicular Fluid Oxidized Low-Density Lipoprotein Levels in Health and Stage III/IV Periodontitis

Study acronym: LDL in GCF
Not Yet Recruiting
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Record status
This record was last updated September 5, 2025 (before its estimated September 15, 2025 completion). Its status may not reflect the trial's current state.
Summary
Periodontitis is a chronic, multifactorial inflammatory disease primarily caused by dysbiotic plaque biofilms, characterized by the progressive destruction of the supporting structures of the teeth. In advanced stages (Stage III/IV), periodontitis leads to significant attachment and bone loss, often culminating in tooth loss and a negative impact on the patient's quality of life. Recent evidence has emphasized the systemic implications of periodontal inflammation, suggesting a bidirectional relationship between periodontitis and various systemic conditions, especially cardiovascular diseases
Trial Details
NCT Number NCT07157878
Lead Sponsor shaimaa hamdy
Conditions Periodontal Diseases, LDL Hyperlipoproteinemia
Enrollment 40 participants
Start Date 2025-09-15
Primary Completion 2025-09-15 (estimated)
Study Completion 2025-09-15 (estimated)
Updated on ClinicalTrials.gov 2025-09-05