Nudge and Motivational Interviewing Interventions to Improve Influenza Vaccine Uptake Among Healthcare Workers in China

The goal of this clinical trial is to learn if nudge-based interventions and motivational interviewing work to improve influenza vaccination uptake among healthcare workers in China. A two-phase randomized controlled trial will be conducted in community hospitals across China, targeting healthcare workers as participants. The main questions are: Do nudge-based interventions increase vaccination rates among healthcare workers? Does motivational interviewing increase vaccination compliance among those who remain unvaccinated after the phase 1? In phase 1, community hospitals will be randomized as units into three arms: standard nudge group, personalized nudge group, and a control group. In phase 2, healthcare workers who remain unvaccinated after phase 1 will be individually randomized to either a motivational interviewing group or a control group. Participants will: Be recruited from community hospitals to participate in the study. In phase 1 (at the early stage of the flu season), community hospitals will be randomly assigned to one of three groups: standardized nudge messages, personalized nudge messages with a chatbot, or no reminders. If still unvaccinated in phase 2 (during peak flu season), healthcare workers will be individually assigned to either motivational interviewing group or receive no extra contact. Have their vaccination status checked at the end of each phase.

NCT Number	NCT07157163
Lead Sponsor	Centers for Disease Control and Prevention, China
Conditions	Influenza Vaccine, Healthcare Workers
Enrollment	4,050 participants
Start Date	2025-09-01
Primary Completion	2026-03 (estimated)
Study Completion	2026-03 (estimated)
Updated on ClinicalTrials.gov	2025-09-11