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Development of Voice Biomarkers of Frequent COVID-19 and Long Covid-related Symptoms Based on Data From Users of the Long COVID Companion App

Study acronym: EVO-LC
StatusRecruiting
PhaseNot specified
Started
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Record History

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  1. Recruitment opened
    • Site details revised
    • Eligibility criteria expanded, about 5 words
    • Study description expanded, about 2 words
  2. Start date: Oct 1, 2025 to Dec 15, 2025v2
  3. Study First Submitted
  • Stopped: an ongoing trial was terminated, suspended or withdrawn.
  • Notable: the trial’s plan changed such as a big move in its timeline or size, a new primary endpoint, sponsor or phase, or recruiting opened or resumed.
  • Minor: routine progress and housekeeping, such as sites added or enrollment closed.
The LIH DDP research team focuses its research topics on vocal biomarkers and Long COVID, among others. Voice is indeed a promising tool to monitor health, as it contains many information on our health and is easy to collect. The development of vocal biomarkers of Long COVID-related symptoms could improve the remote monitoring of the health status of people affected by this disease. The LIH developed the Long COVID Companion (LCC) app in collaboration with the ApresJ20 Long COVID patient association in France to support patients in their daily lives. LCC app users will be invited to participate in this study to collect voice recordings at the same time as health-related data. The objectives of this study are: Primary objective: To develop vocal biomarker candidates for the main Long COVID symptoms (fatigue, brain fog, respiratory problems, sleep issues, stress, anxiety,..) in a population of people with Long COVID. Secondary objectives: * to assess the intra-individual longitudinal evolution of voice characteristics of people with LC * to assess app usability and acceptability in the long-term.
Trial Details
NCT Number NCT07156994
Lead Sponsor Luxembourg Institute of Health
Conditions
(from sponsor)		 Long COVID
Related terms Post-Acute COVID-19 Syndrome
Enrollment 300 participants
Start Date
Primary Completion (estimated)
Study Completion (estimated)
Updated on ClinicalTrials.gov